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ACADEMIC PRESS INC neuroprotective therapeutic strategies
Neuroprotective Therapeutic Strategies, supplied by ACADEMIC PRESS INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/neuroprotective+therapeutic+strategies/neuroprotective+therapeutic+strategies/pm08797665-9-18-25
Average 90 stars, based on 1 article reviews
neuroprotective therapeutic strategies - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Prevention of dopamine-induced cell death by thiol antioxidants: possible implications for treatment of Parkinson's disease.
Article Snippet: We have recently shown that dopamine (DA) can trigger apoptosis, an active program of cellular selfdestruction, in various neuronal cultures and proposed that inappropriate activation of apoptosis by DA and or its oxidation products may initiate nigral cell loss in Parkinson’s disease (PD).. Since DA toxicity may be mediated via generation of oxygen-free radical species, we examined whether DA-induced cell death in PC12 cells may be inhibited by antioxidants.. We have found that the thiol containing compounds, reduced glutathione (GSH),N-acetyl-cysteine (NAC), and dithiothreitol (DTT) were markedly protective, while vitamins C and E had lesser or no effect.



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